The action gets started Thursday night in an NFC West tilt as the Los Angeles Rams (3-1) host the San Francisco 49ers (3-1), who are ravaged with injuries and come into this game after their first loss this year. The 'Niners will be without quarterback Brock Purdy (toe injury) among many others on offense and defense and that will be a big factor in this one.
On Sunday in Philadelphia, the unbeaten Eagles (4-0) take on the Denver Broncos (2-2) and their rugged defense. Philadelphia has been struggling offensively (ZERO pass yards last week in the second half) but still managed to win all their games so far. Look for this game to likely go down to the wire and the Eagles using the "tush push" play to decide the outcome.
The Seattle Seahawks are 3-1 and will host the Tampa Bay Buccaneers (3-1) in what could be the most competitive game this weekend. The Bucs struggled early last week in their loss to the Eagles, but QB Baker Mayfield always brings the fire and passion into the game, so the Seahawks defense will be tested. Can Seattle's offense make it happen enough against Tampa Bay's defense to win this one?
Another game out west will feature the Washington Commanders (2-2) facing the Los Angeles Chargers (3-1), who are coming off a tough loss against the New York Giants. Jayden Daniels is expected to start at quarterback for Washington in this game after missing two weeks with a knee sprain. The Chargers defense will look to pressure him and take away the running game. On offense, the 'Bolts must protect QB Justin Herbert, who threw two interceptions last Sunday. If rookie running back Omarion Hampton gets it going, look for the Chargers to win.
The Sunday night game in Buffalo will have the Bills, the only other NFL unbeaten team at 4-0 (like Philadelphia) facing the New England Patriots (2-2) who put a beat down on the Carolina Panthers last week. The Bills defense must get after Pats QB Drake Maye if they are going to win this game. On offense, look for Josh Allen and company to put up plenty of points, so this game could go down to the wire if the Patriots offense can keep up.
On Monday Night Football, the Kansas City Chiefs (2-2) travel to play the upstart Jacksonville Jaguars (3-1) in what could be a very entertaining game. Chiefs QB Patrick Mahomes has some weapons back in the offensive attack and it showed big time last week in their rout of the Baltimore Ravens, including four touchdown passes from Mahomes to four different teammates. Jacksonville has been playing strong defense so far this season and doing just enough on offense to make the difference.
The rest of the games in Week Five are in the capsule style format and the Heftyinfo picks follow up.
Minnesota Vikings (2-2) vs. Cleveland Browns (1-3) - (game played in London, England) - The Vikings have been overseas for two weeks and are itching to get back home. The Browns play defense, so they could hang around in this one.
Las Vegas Raiders (1-3) at Indianapolis Colts (3-1) - Looks like a blowout on paper for the host Colts . . . but the Raiders pass rush could force Indy QB Daniel Jones into some mistakes. Beware!
New York Giants (1-3) at New Orleans Saints (0-4) - Giants rookie QB Jaxson Dart is coming off a big win in his first start, but he better not be too cocky coming into this game.
Dallas Cowboys (1-2-1) at New York Jets (0-4) - Can the Cowboys light up the scoreboard again this week? The Jets need to hit the reset button, because they have been a disaster so far this season.
Miami Dolphins (1-3) at Carolina Panthers (1-3) - Toss up in this one.
Houston Texans (1-3) at Baltimore Ravens (1-3) - The Ravens are so banged up with injuries it is beyond ridiculous. The Texans have struggled so far, so they could be just the tonic that is needed for Baltimore to get back on the winning side.
Tennessee Titans (0-4) at Arizona Cardinals (2-2) - Cardinals should get it done at home against a terrible Titans teams, but they seem to find ways to hurt themselves in crucial moments of games.
Detroit Lions (3-1) at Cincinnati Bengals (2-2) - The Lions have restored the roar and they are the bigger cats in this one. Bengals defense would do well to prevent 40-plus points this weekend.
The Heftyinfo picks for Week Five . . . . . . . . . . . (Home teams are listed in bold; Lock of the Week is listed in BOLD CAPS)
L.A. Rams over San Francisco
Minnesota over Cleveland (game played in London, England)
Indianapolis over Las Vegas
New Orleans over N.Y. Giants
Dallas over N.Y. Jets
Philadelphia over Denver
Miami over Carolina
Baltimore over Houston
Arizona over Tennessee
Seattle over Tampa Bay
DETROIT over Cincinnati
L.A. Chargers over Washington
Buffalo over New England
Kansas City over Jacksonville
Last Week's Record - 10-5-1
SEASON RECORD - 42-21-1
Lock of the Week Record - 4-0
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